Much like grapefruit, drugs often known as cytochrome P450 (CP450) inhibitors and substrates can hold off the effects of sildenafil and improve your probability of enduring Unintended effects. CP450 inducers, such as modafinil, cut down the results of sildenafil if taken at the same time.
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Sildenafil is in a class of medicines called PDE5 inhibitors. These prescription drugs limit the action of phosphodiesterase enzymes, which break down cyclic guanosine monophosphate.